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Conventional assays rely on a comparable transformation of
2021-06-25

Conventional assays rely on a comparable transformation of the target analytes and the structurally similar (but not identical) proxy substrates and are commonly used to measure individual enzyme activities in (pre-treated) intact sludge flocs (Burgess and Pletschke, 2008a, Gessesse et al., 2003, Yu
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na inhibitor The main advantage of exploiting paper
2021-06-25

The main advantage of exploiting paper sludges as sources of cellulose-derived energy and chemicals in comparison to other lignocellulose substrates is their amenability, which is associated with an extensive pulping process that removes the majority of the lignin and exposes na inhibitor fibers to
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These studies established IAP proteins
2021-06-25

These studies established IAP proteins as dimeric RING E3 ligases, but did not account for the essential role of dimerization. In IAPs and related E3s, such as RNF4 and MDM2, dimerization not only depends on contacts from the core RING domain but also residues N- and C-terminal to the RING domain (B
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For this reason we hypothesized that the
2021-06-25

For this reason we hypothesized that the DHFR gene could be a potential candidate in clefting. Our data, obtained using a family-based association approach, evidenced an association with borderline significance for the SNP rs1677693. The variant allele A at this marker seems to reduce the risk of C
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br Experimental section br Author contributions
2021-06-25

Experimental section Author contributions Acknowledgements Introduction Many SAG supplier synthesis in cells are sequential enzymatic reactions where the product of one enzyme serves as the substrate of a second enzyme (1, 2). Experimental evidence suggests that some of these consecutiv
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Models and theories The CPA equation of state
2021-06-24

Models and theories The CPA equation of state is composed predominantly of two parts: physical item and the association item based on the thermodynamic perturbation theory [21], [22], [26], [27]. The physical item is used to represent intermolecular physical interaction, usually representing the SR
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br Selection of ions for GaN Systems
2021-06-24

Selection of ions for GaN Systems sample test Sample construction analyses has been provided to analyze the beam penetration of several ions of the cocktail in the component. An X-ray and optical view of GaN System devices parts is presented at Fig. 5, Fig. 6 respectively. The drain and source el
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br Particle swarm optimization for NLBP br Computational tes
2021-06-24

Particle swarm optimization for NLBP Computational tests Conclusions Acknowledgements This work was supported by the State Key Development Program for Basic Research of China (No. 2009CB421104) and the National Natural Science Foundation of China (Nos. 50809004 & 41071323). Main Text
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Lenalidomide hydrochloride Finally we demonstrated for the f
2021-06-24

Finally, we demonstrated for the first time that the physiological combinations of estradiol and progesterone levels of premenopausal and postmenopausal women efficiently stimulated the growth of T47D spheroids while clinically relevant concentrations of TPA and UPA suppressed the growth of T47D sph
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We obtained two bands in RT PCR
2021-06-24

We obtained two bands in RT-PCR for detection of SERPIN1-FOSB fusion when Taq DNA polymerase was used (Fig. 3A). Genuine RT-PCR product of SERPIN1-FOSB fusion was proved to be the shorter one (733 RF 9 pairs) by sequencing, and the longer band (863 base pairs) was shown to be derived from native SER
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br Methods br Results and
2021-06-24

Methods Results and discussion Conclusions Conflict of interest Acknowledgment The research is supported by the National Natural Science Foundation of China (Grant No. U1603285). Overview of the MAPK pathway The mitogen-activated protein kinases (MAPK) pathway, often known as a ca
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br STAR Methods br Author Contributions br Acknowledgments T
2021-06-24

STAR★Methods Author Contributions Acknowledgments The authors thank Monika Kuhn for excellent technical assistance and Dr. Antje Schäfer for valuable scientific input. H.S. was supported by the DFG (FZ 82; Graduate School of Life Sciences and SCHI 425-6/1), and A.V.S. by Northwestern Univer
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The role of ETB clearing receptors
2021-06-24

The role of ETB clearing receptors has been studied in detail in endothelial cell–specific ETB knock-out mice. In these animals, clearance of an intravenous Eplerenone receptor of labeled ET-1 was reduced significantly compared with wild-type controls. Importantly, functioning ETB were retained on a
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Using HPLC and an amino acid sequencer the
2021-06-24

Using HPLC and an amino Sodium Phenylbutyrate sequencer, the site of cleavage into the fluorogenic substrate AbzFRQEDDnp, determined as specific to the endopeptidase STH2, was analyzed and identified as being R2-Q3, and into substrate AbzFGQEDDnp, determined as specific to SH1, it was G2-Q3 (Fig. 5,
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It has been reported about the synthesis of
2021-06-23

It has been reported about the synthesis of benzyl bromide in our previous reports, as shown in , , The synthetic route of compounds – is depicted in , Briefly, the synthesis of pyrimidinedione derivatives was started from commercially available pergolide sale . After alkylation of material with
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